T2* Measurement of Myocardial Iron in Thalassemia (Part III)

T2* Measurement of Myocardial Iron in Thalassemia (Part I)

T2* Measurement of Myocardial Iron in Thalassemia (Part II)

Keywords: Thalassemia, hemochromatosis, hemosiderosis, iron overload, Kupffer cells

Source:

Hussain SM. Thalassemia with Iron Deposition. In: Liver MRI. Springer: Berlin Heidelberg, 2007; 180-181.

T2* Measurement of Myocardial Iron in Thalassemia (Part II)

T2* Measurement of Myocardial Iron in Thalassemia (Part I)

Note: Data in Figure 1 are hypothetical.

If you need a copy of the relevant paper for reference, email me and I'll send you one.

T2* Measurement of Myocardial Iron in Thalassemia (Part I)

If you need further details on getting the exponential trendline, feel free to let me know.

You may refer to Part II of this post for the derivation of T2* values.

References:

Leung et al. Magnetic resonance imaging assessment of cardiac and liver iron load in transfusion dependent patients. Pediatr. Blood Cancer (2009) vol. 53 (6) pp. 1054-1059

Westwood et al. Intercentre Reproducibility of Magnetic Resonance T2* Measurements of Myocardial Iron in Thalassaemia. The international journal of cardiovascular imaging (2005) vol. 21 (5) pp. 531-538

Westwood et al. A single breath-hold multiecho T2* cardiovascular magnetic resonance technique for diagnosis of myocardial iron overload. J. Magn. Reson. Imaging (2003) vol. 18 (1) pp. 33-9

Westwood et al. Interscanner reproducibility of cardiovascular magnetic resonance T2* measurements of tissue iron in thalassemia. J. Magn. Reson. Imaging (2003) vol. 18 (5) pp. 616-620

Anderson. Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload. European Heart Journal (2001) vol. 22 (23) pp. 2171-2179